Lizne
Click here for clinics where treatment is available
Regenerate your skin to its youthful state
Skin regeneration skin booster

Lizne is a skin regenerating skin booster formulation whose main ingredient is polynucleotide (PN), also known as salmon injection. The purity of polynucleotide (PN) has been increased to 99%, and since it contains fewer impurities, it causes less pain and redness than Rejuran.
In addition, polynucleotide (PN) is an ingredient that promotes skin regeneration and repair, so it is expected to improve skin firmness, elasticity, and texture.
Find the Right Treatment for You
- Those who want firmer and more elastic skin
- Those who want to improve their skin quality
- Those who want to improve fine lines
- Those who are concerned about acne scars
Supervisor information

Tsubasa Shirozu
- 2010
- Graduated from Hiroshima University School of Medicine, Department of Medicine.
Worked at Saga Prefectural Hospital, Kyushu University Hospital, JCHO Kyushu Hospital, Fukuoka Red Cross Hospital, Kitakyushu Municipal Medical Center, Oita Prefectural Hospital, Kyushu Medical Center
- 2020
- Cosmetic dermatology Elm Clinic Fukuoka Clinic
- Juvederm Vista certified doctor
- Botox Vista certified doctor
- Cosmetic Ingredient Test Level 1
What is LIZNE?
LIZNE is a skin regenerating skin booster formulation whose main ingredient is polynucleotide (PN). This product was developed after the patent of the famous Rejuran expired, and is positioned as an improved version that has improved its shortcomings.
The name LIZNE combines the words LIZ (Leeds): prime + Rene: rebirth, and was chosen with the idea of being reborn as the skin of your youth.
Polynucleotide (PN) is extracted from the DNA of salmonids, and its purity has been increased to 99%. For this reason, it is also called salmon injection. Polynucleotide (PN) is an ingredient that promotes skin regeneration and repair, and is expected to improve the firmness, elasticity, and texture of the skin. Since it is similar to human DNA, it is highly biocompatible and has a low risk of side effects such as foreign body reactions.

Features of LIZNE
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Point
Redness and pain reduction
LIZNE uses high-purity PN extraction and purification technology to increase PN purity to 99%, and clinical trials have shown that it causes relatively little pain because impurities are removed.
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Point
Skin quality improvement effect
The main ingredient, polynucleotide (PN), is expected to improve skin quality. It activates cells, promotes tissue repair and regeneration, and leads to firmer, radiant skin. In addition, its anti-inflammatory effect improves acne scars and scars, and its antioxidant effect suppresses melanin production, leading to a brighter skin tone with a clear, even texture without dullness.
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Point
Improvement of wrinkles
The main ingredient, polynucleotide (PN), is expected to have the effect of improving fine lines and nasolabial folds. Unlike hyaluronic acid, it does not fill in dents, but rather improves the skin quality itself and has an anti-aging effect by activating cells.
Disadvantages of LIZNE
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No immediate effect on wrinkles
LIZNE does not fill in wrinkles like hyaluronic acid, so wrinkles will not improve immediately after treatment.
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Requires several treatments
Since one treatment with LIZNE will not produce visible changes, we recommend three to four consecutive treatments at intervals of about once every two to three weeks. Although the benefit is that the condition improves gradually without being noticed by those around you, those who want to see results in a short period of time may find the lack of immediate effect to be a disadvantage.
Treatment overview
Duration of treatment | 10 to 15 minutes |
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pain | I have a slight tingling pain. |
down time |
Immediately after the procedure, redness, swelling, and in some cases internal bleeding may occur. However, this usually subsides within a few days and will improve within 1 to 2 weeks. |
make | This is possible immediately after the procedure. |
Points to note | On the day of treatment, avoid long baths, excessive alcohol consumption, and strenuous exercise. |
Side effects | You may experience redness, swelling, internal bleeding, itching, pain, etc. These symptoms will generally improve naturally within a few days to a week. |
Treatment interval | We recommend 2 to 3 treatments, with intervals of approximately once every 1 to 3 weeks. |
*Pain, downtime, and effects vary from person to person.
*The treatment time does not include counseling time.
*Pregnant women cannot undergo any treatments.
Flow of treatment
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Flow of treatmentby doctors and nurses
Counseling
(About 30 minutes)At our hospital, we place great emphasis on counseling provided by doctors.Patients who visit us for the first time always receive counseling from a doctor.We will ask you about the symptoms and areas of concern, provide advice tailored to the patient, and decide on a treatment plan.If you have any questions or concerns about the treatment, please feel free to ask.*For those who only need counseling, the session ends here.
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Flow of treatmentDisinfection & anesthesia
Disinfect the injection site.If you have makeup on, you only need to wipe off the area to be injected, so there is no need to remove all makeup.If you are concerned about pain, please feel free to let us know as we will administer topical anesthesia.
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Flow of treatmentTreatment
(About 10 minutes)LIZNE treatments are performed by doctors. In consideration of the patient's privacy, treatments are performed in a completely private room, so please rest assured.
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Flow of treatmentwelcome home
After the treatment, you can go home with your makeup on.There is almost no downtime, so you can immediately return to your daily routine, such as applying makeup or taking a bath.
Clinics where treatment is available
For those who live in the Kansai region
Lizne rates
(tax included)Menu | Regular fee | pack fee |
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LIZNE 1cc | 49,800JPY | XNUMX times 134000JPY XNUMX times179,000JPY |
Surface anesthesia | 3,300JPY | - |
Click here for details on the fees for each treatment
About Payment Methods
You can choose the payment method that suits you.
Various combinations are possible.
- Lump sum cash
- Credit Transfer
- Medical loan(3 to 60 installments/annual interest rate 8.4%)
For minor patients
If you are a minor, a "parental consent form" is required.Please download and fill out the form in advance and bring it with you, or bring one of your parents with you.
Clinics where treatment is available
For those who live in the Kansai region

Hiroshi Kikuchi
- 2008
- Graduated from Hiroshima University School of Medicine, Department of Medicine Worked at Chiba University School of Medicine Affiliated Hospital and related hospitals.
- 2013
- Cosmetic dermatology Elm Clinic Fukuoka clinic opened
- Juvederm Vista certified doctor
- Botox Vista certified doctor
- Cosmetic Ingredient Test Level 1
About medical advertising guidelines
Review and improvement of homepage
At Elm Clinic, under the supervision of a doctor, we are reviewing and improving our website as appropriate in the following two areas, in accordance with the "Medical Advertising Guidelines."
(i) Addition/deletion of testimonials
(ii) When posting case photos, please describe the details of the treatment, risks of the treatment, price of the treatment, etc.
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[Business hours] 9:00-18:00 [Closed] Sundays
*Temporary closures may be established.[Business hours] 10:00-19:00 [Closed days] Irregular holidays
*Temporary closures may be established.[Business hours] 9:00-18:00 [Closed] Sundays
*Temporary closures may be established.[Business hours] 10:00-19:00 [Closed days] Irregular holidays
*Temporary closures may be established.[Business hours] 9:00-18:00 [Closed days] Irregular holidays
*Temporary closures may be established.Monday/Thursday 11:00-20:00/Others 10:00-19:00
[Regular holidays] Irregular holidays
[Business Hours] 9: 00-18: 00
[Closed] Sundays and Mondays
[Business Hours] 9: 30-18: 30
[ Regular holiday ]Sunday
Weekdays 10:00-19:00 Saturdays, Sundays and holidays 9:30-18:30
[Regular holidays] Irregular holidays
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