Plureal
Densify series
Click here for clinics where treatment is available
Achieving “strong and beautiful skin from deep within”

"Plurial Densifier Series" is a type of filler that increases the moisture content deep inside the skin and improves firmness, elasticity, and smooth skin quality, but it can also enhance the skin's natural self-repairing ability and strengthen the skin's original structure. A new Biostimulator formulation.
Plurial Densify series is recommended for the following people
- Want to improve your skin's moisture, firmness, and elasticity?
- Concerned about fine lines around the eyes and mouth?
- I want to improve scars such as stretch marks and stretch marks.
- Want to improve dry skin such as atopic dermatitis?
Supervisor information

- Graduated from Hiroshima University School of Medicine, Department of Medicine.
Works at a hospital in Tokyo
- Cosmetic Dermatology Elm Clinic Kyoto Clinic Works
- Japanese Society of Aesthetic Dermatology
- Juvederm Vista certified doctor
- Botox Vista certified doctor
What is “Plurial Densifier Series”?
"Plurial Densify series" is a bioremodeling preparation (biostimulation) specialized for skin regeneration. This is a filler series developed by MD Skin Solutions in Luxembourg, and is an injection agent (non-crosslinked hyaluronic acid) that has received CE approval.
By injecting it, you can expect to increase the amount of moisture deep inside your skin, improving firmness, elasticity, and smooth skin quality. This is a new Biostimulator formulation that can further promote collagen production, enhance the skin's natural self-repair ability, and strengthen the skin.

Features of “Plurial Densifier Series”
PLURYAL SILK
PLURYAL SILK is the world's first PN (polynucleotide) formulation to receive CE approval specifically for the eye area.
The product has been designed to be safer by increasing the purity of PN using a polynucleotide (PN) preparation and completely removing proteins, which greatly reduces the risk of allergies. It can be injected into areas with thin skin or delicate areas of the face, and is effective for repairing dark circles, fine lines, and scars. In addition, PN (polynucleotide) preparations have been reported to have a number of effects on skin regeneration, such as moisturizing the skin by producing collagen, promoting VEGF secretion, promoting angiogenesis, and antioxidant effects.
*As an initial treatment, 3 times every 3 weeks is recommended.

PLURYAL DENSIFY
PLURYAL DENSIFY is composed of a mixture of PN (polynucleotide), which has a skin repair effect, HA (non-crosslinked hyaluronic acid), which improves moisture and elasticity, and mannitol, which has an antioxidant effect and suppresses the decomposition of HA. It has been. It improves skin quality and makes the skin smoother, and has a proven track record of rejuvenating skin age overseas. Plurial Silk is suitable for injection into delicate areas such as around the eyes, while Plurial Densify is suitable for injection into the entire face, neck, décolletage, etc.
*As an initial treatment, 3 times every 3 weeks is recommended.

Features and benefits of Plureal Densifier series
-
Point
Strengthen the skin's natural strength
Plureal Densify series is a type of filler that increases the moisture content deep inside the skin, gives skin firmness and elasticity, and improves skin quality. Unlike conventional fillers, it is a bioremodeling agent (biostimulation) that can promote collagen production, supplement the skin's natural self-repair function, and strengthen the skin's original structure.
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Point
skin age rejuvenation
The Plurial Densify series, which is attracting attention overseas, has many achievements in improving the overall skin texture, fine wrinkles, and firmness, and rejuvenating the skin's age. There are also experimental reports showing that those who received the injections had their skin rejuvenated by -15 years.
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Point
Safety
By completely removing proteins that tend to cause allergic reactions, the formulation has been designed to greatly reduce the risk of allergies and improve safety. Injection treatment is used by many people.
Treatment overview
Duration of treatment | 60 to 90 minutes |
---|---|
pain | Depending on the area, you may experience a slight tingling pain or a dull pain during injection. |
down time |
Immediately after injection, there will be some unevenness at the injection site, but in most cases it will disappear the next day or several days later. Internal bleeding may occur.Internal bleeding will gradually improve over about two weeks. |
make | This is possible from the next day. |
Precautions | Please refrain from using facial cleansing foam on the day of treatment. |
Side effects | There are almost no side effects.In rare cases, redness, induration, swelling, or swelling may occur, but this will subside in about a week. |
Treatment frequency | It is recommended that you undergo treatment approximately 3 times at intervals of XNUMX weeks, and then maintain treatment once every XNUMX months. |
*Pain, downtime, and effects vary from person to person.
*The treatment time does not include counseling time.
*Pregnant women cannot undergo any treatments.
Flow of treatment
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Flow of treatmentCounseling
Before the procedure, you will have a consultation with your doctor.During the consultation, you will receive a detailed explanation of the treatment area, effects, risks, costs, and aftercare.
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Flow of treatmentDisinfection/anesthesia
Disinfect before the treatment. If you wish, we will administer topical anesthesia (about 30 minutes).
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Flow of treatmentPlurial Densifer series injection
The doctor will inject Plureal Densify series. The amount and location of injection will be determined based on what was determined during the consultation.
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Flow of treatmentEnd of treatment
After the treatment, we will explain the aftercare.Please refrain from wearing makeup on the day of your appointment.
Clinics where treatment is available
Residents of Kanto (Tokyo)
For those who live in the Chugoku region
For those who live in Kyushu
Plureal Densify series
(tax included)Menu | One time fee | Courses |
---|---|---|
Pullial Silk 1 piece [Hiroshima Clinic, Okayama Clinic, Kyoto Clinic, Kumamoto Clinic, Osaka Clinic, Azabu Clinic] | 49,800JPY (+10,000 yen with Botox addition) |
3 times 130,000JPY |
Plureal Densify 1 bottle | 59,800JPY (+10,000 yen with Botox addition) |
3 times 160,000JPY |
Pullial Densify 2 bottles [Hiroshima Clinic, Okayama Clinic, Kyoto Clinic, Kumamoto Clinic, Osaka Clinic, Azabu Clinic] | 109,800JPY (+10,000 yen with Botox addition) |
3 times 293,000JPY |
Pullial Silk x 1 + Densify x 1 [Hiroshima Clinic, Okayama Clinic, Kyoto Clinic, Kumamoto Clinic, Osaka Clinic, Azabu Clinic] | 99,800JPY (+10,000 yen with Botox addition) |
3 times 279,000JPY |
Surface anesthesia | 3,300JPY | - |
Click here for details on the fees for each treatment
About Payment Methods
You can choose the payment method that suits you.
Various combinations are possible.
- Lump sum cash
- Credit Transfer
- Medical loan(3 to 60 installments/annual interest rate 8.4%)
For minor patients
If you are a minor, a "parental consent form" is required.Please download and fill out the form in advance and bring it with you, or bring one of your parents with you.
FAQ
- How long does it take to see effects after injecting Plurial Densify series?
- If you perform the treatment once every three weeks, the third treatment is the standard.
- Can I go to work the next day?
- Internal bleeding may occur, but you can wear makeup the next day and hide it with concealer.
- Do you have any pain?
- Before the procedure, you will be given a topical anesthetic.Since this is an injection treatment, you may feel a slight pain depending on the location.
Clinics where treatment is available
Residents of Kanto (Tokyo)
For those who live in the Chugoku region
For those who live in Kyushu

Hiroshi Kikuchi
- 2008
- Graduated from Hiroshima University School of Medicine, Department of Medicine Worked at Chiba University School of Medicine Affiliated Hospital and related hospitals.
- 2013
- Cosmetic dermatology Elm Clinic Fukuoka clinic opened
- Japanese Society of Aesthetic Dermatology
- Juvederm Vista certified doctor
- Botox Vista certified doctor
- Cosmetic Ingredient Test Level 1
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Review and improvement of homepage
At Elm Clinic, under the supervision of a doctor, we are reviewing and improving our website as appropriate in the following two areas, in accordance with the "Medical Advertising Guidelines."
(i) Addition/deletion of testimonials
(ii) When posting case photos, please describe the details of the treatment, risks of the treatment, price of the treatment, etc.
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*Temporary closures may be established.[Business hours] 10:00-19:00 [Closed days] Irregular holidays
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